How does ICSI Fertility Treatment Centers differ from IVF?
IVF stands for in vitro fertilization wherein the fertilized egg will then undergo the embryo transfer after it has become an embryo. The female partner in the case of IVF Fertility Treatment Centers will undergo egg retrieval surgery in vitro fertilization. The man’s sperm is then placed on the eggs in a dish. The natural fertilization process can occur in this way.
The fertilized egg will then undergo embryo transfer. IVF Fertility Treatment Centers are where the female partner will have egg retrieval surgery. After that, the man’s sperm is added to the eggs in a dish in vitro fertilization Fertility Treatment Centers. The eggs are then fertilized naturally.
The embryo created by ICSI Fertility Treatment Centers is then placed in the woman’s uterus. ICSI Fertility Treatment Centers is generally only used when there is a problem with the sperm. This might be because the man has a low sperm count or poor motility. If ICSI Fertility Treatment Centers are used, the sperm will be injected into the egg using a very fine needle.
When Do ICSI Fertility Treatment Centers Apply ICSI?
ICSI Fertility Treatment Centers are used when:
- A couple has problems with sperm count, poor motility, abnormal sperm morphology, or other male infertility factors.
- Sperm need to be surgically retrieved from the testicles (azoospermia)
- Failed fertilization during previous IVF cycles
- Utilizing donor eggs or frozen sperm where fertilization may be more unpredictable
Success Rates
The success rate of IVF procedures is about 50–70% fertilization, while ICSI procedures are about 70–80% fertilization. This is a significant difference and can increase your chances of fertilization if you have male-factor infertility.
Studies suggest that among couples without male-factor infertility, there is a trend toward higher implantation and live birth rates for standard IVF compared to ICSI, which may be due to embryo quality.
Genetic Screening & Embryo Selection
PGT techniques have rapidly advanced, and sophisticated polygenic screening panels can now detect hundreds of disease risks and traits. However, such expanded testing raises complex ethical and accuracy concerns.
The two genetic tests can be used with either ICSI or IVF; however, the biopsy procedure to obtain the cell samples is cleaner and easier to perform when only the injected sperm is present under ICSI.
Procedure Complexity & Lab Requirements
ICSI Fertility Treatment Centers require a certain level of technology and a highly trained embryologist who is skilled in micromanipulation techniques. The procedure requires combining just a single sperm with the egg, using special equipment to immobilize the egg, and then inserting the sperm through a very fine needle.
ICSI Fertility Treatment Centers also take more time in the lab than standard IVF. After the ICSI Fertility Treatment Centers procedure is complete, the embryo is then transferred to the uterus using the standard embryo transfer procedure.
Evidence among severe male-factor couples (e.g., non-obstructive azoospermia) has demonstrated that fertilization was successful in about 69–70% of cycles when using ICSI Fertility Treatment Centers, and the cumulative pregnancy and live birth rates were almost half (46–47%) of couples.
Embryo Quality
The primary concern with both IVF and ICSI Fertility Treatment Centers bypassing natural selection is that the resulting embryo quality may be poor. This is not the case, however. Research using sibling oocyte design showed that embryo morphology and quality were dependent on intrinsic gamete factors more so than fertilization technique.
ICSI is, therefore, likely to result in higher fertilization rates, but the embryo quality of these fertilized eggs is no different from that of standard IVF.
Genetic Testing
Genetic testing technologies such as preimplantation genetic testing (PGT) have now been integrated into both IVF and ICSI Fertility Treatment Centers’ treatment protocols. While most clinics will recommend that preimplantation screening be done.
To reduce miscarriage risk or identify aneuploidies or other chromosomal abnormalities, research has shown that among average-risk patients, the use of PGT-A does not improve the live birth rate. It may actually be associated with lower live birth rates.
Clinics have done PGT under ICSI Fertility Treatment Centers with the belief that it may be necessary to ensure only the desired sperm is used. But most clinics now biopsy for PGT testing without the need for ICSI. So, ICSI Fertility Treatment Centers is not always necessary.
Advancements: Sperm Selection and Robotic ICSI
Improved sperm selection has continued to be a key area of innovation for improving outcomes from ICSI. IMSI is a procedure that uses ultra-high magnification to visualize sperm morphology and select the highest quality sperm for injection. The technique has been shown to improve pregnancy rates and decrease miscarriage risk when using sperm with high DNA fragmentation.
Automated ICSI has been in development for some time, but a recent high-profile birth report from Japan using the R-One robot revealed the first published data. In a pilot study, four of the five injected eggs fertilized, resulting in a healthy birth.
Risks and Genetic Implications
The risks associated with IVF and ICSI are very similar, such as OHSS and ectopic pregnancy. However, a slight increased risk of birth defects has been noted with ICSI Fertility Treatment Centers, particularly chromosomal abnormalities.
Reach out!
At Sairaksha Fertility Centre we provide caring, personalised solutions whether you need intracytoplasmic sperm injection (ICSI) or regular in vitro fertilization (IVF), Our team is here to help you on your journey to parenthood.
FAQs
Does ICSI help sperm count poor?
A: Yes. it is often regarded that ICSI will be helpful if your sperm count poor. ICSI makes use of an injection of a single sperm into the egg.
Is embryo transfer the same after IVF or ICSI Fertility Treatment Centers?
A: Yes. After IVF or ICSI, the embryo transfer procedure is the same.
Does ICSI Fertility Treatment Centers include full infertility treatment care?
A: Yes. ICSI Fertility Treatment Centers include all the aspects of infertility treatment. These are ovarian stimulation, egg retrieval, intracytoplasmic sperm injection(ICSI), embryo culturing, genetic testing support, embryo transfer, and pregnancy follow-up.
Which treatment will be effective for you?
A: If you have male-factor infertility or if you have had any previous IVF cycles fail, ICSI Fertility Treatment Centers is the most effective treatment for you.